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Seville — Neighborhood Guide

Best Hotels in Santa Cruz, Seville

Santa Cruz is Seville's former Jewish quarter and its most seductive neighbourhood — a maze of white-washed alleyways, hidden plazas draped in bougainvillea, and the city's highest concentration of historic hotels and flamenco venues. The Alcázar and Cathedral rise at its edge.

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Best Hotels in Santa Cruz, Seville

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The Best Hotels in Santa Cruz, Seville at a Glance

Santa Cruz is Seville's former Jewish quarter and its most seductive neighbourhood — a maze of white-washed alleyways, hidden plazas draped in bougainvillea, and the city's highest concentration of historic hotels and flamenco venues. The Alcázar and Cathedral rise at its edge.

  1. 1
    Hotel Alfonso XIII Santa Cruz · $$$$ · ★ 9.4 Superb
  2. 2
    Casa 1800 Sevilla Santa Cruz · $$$ · ★ 9.5 Superb
  3. 3
    Hospes Las Casas del Rey de Baeza Santa Cruz · $$$ · ★ 9.0 Superb
  4. 4
    EME Catedral Hotel Santa Cruz · $$$ · ★ 8.8 Excellent
  5. 5
    Hotel Simón Santa Cruz · $$ · ★ 8.5 Excellent

8 hotels reviewed · Price range: $$$$, $$$, $$ · Last updated March 2026

About This Guide

Staying in Santa Cruz puts you at the heart of what makes Seville special. The neighborhood offers a unique blend of local character and visitor-friendly amenities. Our hotel picks range from intimate boutiques to polished luxury properties, each chosen for its ability to connect you with the authentic Santa Cruz experience.

Insider Tips

  • 1

    The best dining in Santa Cruz is usually one street back from the main tourist thoroughfare.

  • 2

    Ask your hotel concierge for their personal favourite spots in Santa Cruz — they often know hidden gems.

  • 3

    Walking is the best way to experience Santa Cruz — most attractions are within a 15-minute stroll.

Our Picks

Best Hotels in Santa Cruz, Seville

8 hotels · Updated February 2026

Hotel Alfonso XIII — Santa Cruz
$$$$ Ultra-luxury
★ 9.4 Superb

The grande dame of Seville — a 1929 neo-Mudéjar masterpiece built for the 1929 Ibero-American Exposition, with a soaring central courtyard, Moorish tilework, and rooms of regal proportions. One of Spain's great historic hotels, and the undisputed address of choice for kings and presidents.

  • Iconic
  • Historic Palace
  • Luxury
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Casa 1800 Sevilla — Santa Cruz
$$$ Upscale
★ 9.5 Superb

An intimate boutique hotel in a 19th-century Sevillian palace steps from the Cathedral, with courtyards planted with orange trees, individually styled rooms using local Mudéjar tilework and antiques, and a rooftop terrace with cathedral views. Impeccably run with outstanding personal service.

  • Boutique Palace
  • Santa Cruz
  • Romance
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Hospes Las Casas del Rey de Baeza — Santa Cruz
$$$ Upscale
★ 9.0 Superb

A sensitively restored cluster of 18th-century townhouses around a columned central courtyard, with a rooftop pool, spa, and rooms that blend whitewashed Andalucían simplicity with modern luxury. The courtyard breakfast under orange trees is one of Seville's great hotel experiences.

  • Courtyard
  • Rooftop
  • Boutique
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EME Catedral Hotel — Santa Cruz
$$$ Upscale
★ 8.8 Excellent

A bold contemporary design hotel spread across several renovated houses directly opposite the Cathedral and Giralda, with a spectacular rooftop bar and pool that commands the best view in Seville. The interiors mix Moorish heritage with a distinctly modern editorial aesthetic.

  • Cathedral View
  • Rooftop Pool
  • Design
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Hotel Simón — Santa Cruz
$$ Mid-range
★ 8.5 Excellent

Santa Cruz

Hotel Simón

One of Seville's most beloved independent hotels, occupying an 18th-century mansion with a classic azulejo-tiled courtyard and rooms varying in size and decoration. The value proposition for this location and character is almost unbeatable in Seville.

  • Character
  • Independent
  • Value
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Hotel Amadeus Sevilla — Santa Cruz
$$ Mid-range
★ 9.0 Superb

A musical-themed boutique in a restored Santa Cruz mansion where rooms are equipped with upright pianos and named after composers, with a rooftop terrace and one of the most welcoming owner-run atmospheres in the city. Beloved by musicians, artists, and romantic travellers.

  • Music Theme
  • Boutique
  • Romance
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Casas de la Judería — Santa Cruz
$$$ Upscale
★ 8.7 Excellent

A labyrinthine complex of 27 connected townhouses threaded through the old Jewish quarter with interior gardens, fountains, and 138 individually furnished rooms. One of Seville's most idiosyncratic and romantic hotel experiences.

  • Jewish Quarter
  • Gardens
  • Labyrinthine
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Hotel Doña Maria — Santa Cruz
$$ Mid-range
★ 8.3 Very Good

A classic Sevillian hotel steps from the Cathedral with a small rooftop pool, ornate Baroque lobby, and antique-furnished rooms at mid-range prices. Perfect for those who want authentic Seville character without the luxury surcharge.

  • Classic
  • Rooftop
  • Historic
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Common Questions

Frequently Asked Questions

Is Santa Cruz a good area to stay in Seville?

Santa Cruz is the best area for first-time visitors — you are within a five-minute walk of the Cathedral, Alcázar, and the best flamenco tablaos, and hotel quality here is exceptional. It can be lively at night but the alleyways absorb the crowds.

What is Santa Cruz known for?

The Real Alcázar palace gardens, the Catedral de Sevilla and Giralda tower, the Plaza de Doña Elvira, authentic flamenco at Casa de la Memoria and El Palacio Andaluz, and some of Spain's most beautiful patios.

How do I get to Santa Cruz from the airport?

The most convenient option is a rideshare (Uber/Lyft), typically 30-50 minutes depending on traffic. Public transport is also available and often more economical.

Ready to book Seville?

Prices and availability change daily. Lock in the best rate by booking early — most of our top picks offer free cancellation.

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