Edinburgh's boutique landscape divides roughly between Old Town properties (which work with historic buildings and often Gothic or baronial design references) and New Town properties (which favour Georgian restraint with contemporary accents). Both have produced excellent results.
Prestonfield House is the most extraordinary boutique property in Edinburgh — not strictly in either Old or New Town, but a 17th-century mansion in the shadow of Arthur's Seat with interiors of baroque excess (Highland cattle in the grounds, taxidermy everywhere, velvet and gilt throughout). It's run by James Thomson, who has created a hotel of genuine personality that couldn't exist anywhere other than Edinburgh.
The Glasshouse Hotel on Leith Street takes a different approach — integrating a historic church facade into a contemporary glass tower to create one of Scotland's most distinctive hotel buildings. The room panoramas of Calton Hill are genuinely spectacular, and the rooftop garden is one of the best outdoor spaces in the city.
Eden Locke on George Street is the New Town boutique entry — apartment-style rooms with kitchen facilities, a neighbourhood-café aesthetic, and a location on Edinburgh's best shopping street. It attracts creative professionals and long-stay visitors rather than one-night tourists, and the quality of the physical space is considerably above what the rates suggest.
Nira Caledonia on Gloucester Place is another New Town gem — two Georgian townhouses joined together with Scottish craft-influenced interiors, a good kitchen-bar, and the quiet, residential character of the Stockbridge fringe that feels authentically local.