Hotelier's Choice

Best Hotels Near Penn Medicine (Hospital of the University of Pennsylvania)

Penn Medicine's Hospital of the University of Pennsylvania is one of America's oldest and most respected academic medical centres, affiliated with the Perelman School of Medicine and consistently ranked in the top five nationally for cancer, cardiac surgery, and neuroscience. The 6 hotels below are the best-rated places to stay within 2.2 km of Penn Medicine (Hospital of the University of Pennsylvania), listed closest first. Guest scores and distances come from Booking.com, checked September 2026.

Our Picks — Philadelphia

The Inn at Penn, A Hilton Hotel — 400 m away from Penn Medicine (Hospital of the University of Pennsylvania)
1 $$$$ Ultra-luxury
★ 8.2 Very Good

About 400 m from Penn Medicine (Hospital of the University of Pennsylvania), roughly a 5-minute walk. Guests score it 8.2 out of 10 across 286 Booking.com reviews.

  • Walkable
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★ 8.2 guest score from 286 Booking.com reviews · Many rooms include free cancellation

Sheraton Philadelphia University City Hotel — 500 m away from Penn Medicine (Hospital of the University of Pennsylvania)
2 $$$ Upscale
★ 8.3 Very Good

About 500 m from Penn Medicine (Hospital of the University of Pennsylvania), roughly a 6-minute walk. Guests score it 8.3 out of 10 across 274 Booking.com reviews.

  • Walkable
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★ 8.3 guest score from 274 Booking.com reviews · Many rooms include free cancellation

Fitler Club — 1.3 km away from Penn Medicine (Hospital of the University of Pennsylvania)
3 $$$$ Ultra-luxury
★ 9.3 Superb

1.3 km away

Fitler Club

About 1.3 km from Penn Medicine (Hospital of the University of Pennsylvania), roughly a 15-minute walk. Guests score it 9.3 out of 10 across 32 Booking.com reviews.

  • Nearby
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★ 9.3 guest score from 32 Booking.com reviews · Many rooms include free cancellation

Four Seasons Hotel Philadelphia at Comcast Center — 1.9 km away from Penn Medicine (Hospital of the University of Pennsylvania)
4 $$$$ Ultra-luxury
★ 9.7 Exceptional

About 1.9 km from Penn Medicine (Hospital of the University of Pennsylvania), roughly a 25-minute walk. Guests score it 9.7 out of 10 across 50 Booking.com reviews.

  • Top rated
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★ 9.7 guest score from 50 Booking.com reviews · Many rooms include free cancellation

Sofitel Philadelphia at Rittenhouse Square — 2.1 km away from Penn Medicine (Hospital of the University of Pennsylvania)
5 $$$ Upscale
★ 8.7 Excellent

About 2.1 km from Penn Medicine (Hospital of the University of Pennsylvania). Guests score it 8.7 out of 10 across 559 Booking.com reviews.

  • Nearby
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★ 8.7 guest score from 559 Booking.com reviews · Many rooms include free cancellation

Hyatt Centric Rittenhouse Square Philadelphia — 2.2 km away from Penn Medicine (Hospital of the University of Pennsylvania)
6 $$$ Upscale
★ 8.6 Excellent

About 2.2 km from Penn Medicine (Hospital of the University of Pennsylvania). Guests score it 8.6 out of 10 across 585 Booking.com reviews.

  • Best value
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★ 8.6 guest score from 585 Booking.com reviews · Many rooms include free cancellation

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