Penn Medicine's Hospital of the University of Pennsylvania is one of America's oldest and most respected academic medical centres, affiliated with the Perelman School of Medicine and consistently ranked in the top five nationally for cancer, cardiac surgery, and neuroscience. Penn Medicine was a pioneer in the development of CAR-T cell therapy for blood cancers, a landmark breakthrough in oncology. Hotels in University City and Center City Philadelphia offer families a comfortable base during treatment at one of medicine's great institutions.
Our Picks — Philadelphia
Perched atop the Comcast Technology Center, this architectural gem offers breathtaking panoramic city views from its sky-high rooms and infinity-edge pool. Michelin-distinguished dining by Jean-Georges and a crystal-infused spa elevate it to a pinnacle of urban luxury.
Rittenhouse Square
Overlooking picturesque Rittenhouse Square, this landmark blends timeless sophistication with modern comforts, including spacious suites and an indoor pool. Renowned Lacroix restaurant serves seasonal French cuisine in an elegant setting.
Center City
Housed in a historic beaux-arts building opposite City Hall, it features luxurious rooms, an extensive spa, and refined dining with city vistas. Classic Ritz-Carlton service meets Philadelphia's cultural heartbeat.
Market East
Stylish apartment-hotel with full kitchens, offering Philly's largest rooftop pool, fitness center, and community garden for a home-like yet upscale vibe. Perfect for longer stays near Reading Terminal Market.
University City
Scholarly boutique hotel amid UPenn and Drexel campuses, featuring cozy library-like spaces, complimentary coffee, and a 24-hour gym. Ideal for academics and culture enthusiasts exploring Philly's innovation hub.
Rittenhouse Row
Trendy apartment-style lodging in a lively dining district, with modern kitchens and communal spaces for a residential feel in the heart of Center City. Balances convenience and style for urban explorers.
Looking for more options? See all Philadelphia hotels