Hotelier's Choice

Best Hotels Near Penn Medicine

University of Pennsylvania Health System — one of the nation's top academic medical centers. The 6 hotels below are the best-rated places to stay within 2.1 km of Penn Medicine, listed closest first. Guest scores and distances come from Booking.com, checked September 2026.

Our Picks — Philadelphia

The Inn at Penn, A Hilton Hotel — 700 m away from Penn Medicine
1 $$$$ Ultra-luxury
★ 8.2 Very Good

About 700 m from Penn Medicine, roughly a 9-minute walk. Guests score it 8.2 out of 10 across 286 Booking.com reviews.

  • Walkable
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★ 8.2 guest score from 286 Booking.com reviews · Many rooms include free cancellation

Sheraton Philadelphia University City Hotel — 800 m away from Penn Medicine
2 $$$ Upscale
★ 8.3 Very Good

About 800 m from Penn Medicine, roughly a 10-minute walk. Guests score it 8.3 out of 10 across 274 Booking.com reviews.

  • Walkable
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★ 8.3 guest score from 274 Booking.com reviews · Many rooms include free cancellation

Fitler Club — 1.3 km away from Penn Medicine
3 $$$$ Ultra-luxury
★ 9.3 Superb

1.3 km away

Fitler Club

About 1.3 km from Penn Medicine, roughly a 15-minute walk. Guests score it 9.3 out of 10 across 32 Booking.com reviews.

  • Nearby
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★ 9.3 guest score from 32 Booking.com reviews · Many rooms include free cancellation

Sofitel Philadelphia at Rittenhouse Square — 2 km away from Penn Medicine
5 $$$ Upscale
★ 8.7 Excellent

About 2 km from Penn Medicine, roughly a 25-minute walk. Guests score it 8.7 out of 10 across 559 Booking.com reviews.

  • Nearby
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★ 8.7 guest score from 559 Booking.com reviews · Many rooms include free cancellation

Looking for more options? See all Philadelphia hotels