Mayo Clinic Arizona in Scottsdale is one of three campuses of the world-renowned Mayo Clinic, ranked the number-one hospital in the United States by US News for multiple years running. The Scottsdale campus offers the full breadth of Mayo's integrated multispecialty care model, including complex cancer treatment, cardiac surgery, and rare disease diagnosis. Scottsdale's resort-style hotels provide exceptional comfort for patients and families who travel to Arizona for the Mayo experience, often combining medical visits with the area's renowned desert scenery.
Our Picks — Scottsdale
Paradise Valley
A desert palace carved into the base of Camelback Mountain with 645 acres of cactus gardens, 11 tennis courts, eight pools including a cactus-pool complex, and a spa that has topped national rankings for decades. The resort's sheer scale and perfection of execution — every detail handled with apparent effortlessness — make it the benchmark for Scottsdale luxury.
North Scottsdale
Perched at the foot of the McDowell Mountains in the most dramatic desert setting in the valley, this Four Seasons property embeds 210 casita-style rooms among boulder formations and native Sonoran flora. The Troon North Golf Club access, Talavera restaurant terrace at sunset, and spa with desert-herb treatments make it the most authentically Arizonan luxury experience.
North Scottsdale / Carefree
Set among 12-million-year-old granite boulder formations in the Sonoran Desert near Carefree, this Waldorf Astoria property is visually unlike any resort on earth — casitas blend so perfectly into the rocks that the landscape seems to have grown the buildings. Two championship golf courses, a world-class spa, and extraordinary star-gazing complete the picture.
Paradise Valley
A 1929 Mediterranean-style hacienda that was Delos Cooke's private estate before becoming Scottsdale's most intimate full-service resort. The 119 casitas nestle among 30-foot royal palms and rose gardens at the foot of Camelback Mountain, and the T. Cook's restaurant — in the original living room — remains one of Arizona's most romantic dinner settings.
Old Town
A design-forward Hyatt property in the Camelback Corridor that blends Southwestern art curation with the brand's signature social-lobby energy — a record library, curated cocktail bar (Weft & Warp), and a pool scene that draws non-guests by name. The 185 bungalow-style accommodations arranged around fire pits and native desert plantings create a genuinely residential resort feel.
Old Town
A restored 1956 modernist icon that once hosted Bing Crosby and Janet Leigh, the Valley Ho has been impeccably renovated into Old Town's most stylish mid-century retreat. The ZuZu restaurant celebrates locally sourced Arizona cuisine, the retro pool scene is genuinely lively, and the architecture — with terrazzo floors and Douglas fir details — is worth the stay alone.
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