The Georgia O'Keeffe Museum in downtown Santa Fe holds the world's largest permanent collection of works by the iconic modernist artist who spent half her creative life in New Mexico — her luminous paintings of desert flowers, skulls, adobe churches, and the New Mexico sky directly connected to the landscape visible from the museum windows. O'Keeffe lived in Abiquiu and Ghost Ranch, both accessible on day trips from Santa Fe. Hotels near the Georgia O'Keeffe Museum are in the historic district, surrounded by the Indian arts, Spanish colonial, and contemporary galleries that make Santa Fe the third-largest art market in the United States.
Our Picks — Santa Fe
Downtown / DeVargas Street (near the Historic Plaza)
A maximalist, jewel-box luxury inn known for richly layered decor, intimate service, and an atmosphere that feels like staying inside an art collector’s Santa Fe home. It’s walkable to the Plaza and delivers a true special-occasion stay with spa-style pampering and standout breakfasts.
Downtown / Historic Plaza area
One of Santa Fe’s most iconic luxury hotels, blending refined Southwest style with a prime Plaza-adjacent location. Expect upscale comfort with signature details like kiva-style fireplaces and an on-site restaurant that’s a go-to even for non-guests.
Eastside / Alameda (near Canyon Road)
A favorite for travelers who want a warm, traditional Santa Fe feel with excellent walkability to Canyon Road galleries and the Plaza. The atmosphere is relaxed and intimate, with cozy common spaces and a stay that feels more like a refined inn than a big hotel.
Near the State Capitol / Eastside edge
A small, historic-feeling adobe-style inn that delivers quiet charm and an easy stroll into the action without the crowds right outside your door. It’s a strong pick for couples and solo travelers who want character, comfort, and a boutique vibe at a more approachable price point.
Downtown / Paseo de Peralta (near the Plaza)
A dependable, traveler-friendly option with a central location and amenities that make longer stays easier. It’s especially appealing for guests who want straightforward comfort close to downtown, plus on-site dining and a pool/hot tub setup for post-sightseeing downtime.
Historic Plaza
A landmark hotel with classic Santa Fe ambiance and one of the city’s best-known locations right on the Plaza. Come for historic character and views, and stay for the easy access to museums, shopping, and dining at the heart of town.
Looking for more options? See all Santa Fe hotels