Best Hotels Near UPMC (University of Pittsburgh Medical Center)

UPMC is one of the nation's leading integrated health care systems, with its flagship Presbyterian Hospital ranked among the top hospitals in the United States and a global pioneer in organ transplantation. Dr. Thomas Starzl performed the world's first successful liver transplant at UPMC in 1967, and the centre continues to lead in multi-organ transplant complexity. Pittsburgh's hotel scene, centred around Oakland and Downtown, provides ample accommodation for patients and families who travel from across the world for UPMC's specialised surgical expertise.

Our Picks — Pittsburgh

Drury Plaza Hotel Pittsburgh Downtown — Downtown
$$
★ 9.1 Superb

Housed in a historic building, this top-rated hotel offers exceptional value with free evening snacks, hot breakfast, and an indoor pool. Guests rave about the central location near stadiums and cultural sites, making it perfect for exploring the city on foot.

  • Indoor pool
  • Free breakfast
  • Historic building
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The Priory Hotel — North Side
$$
★ 9.0 Superb

A unique boutique stay in a converted 19th-century monastery, featuring Italian villa-style gardens and antique furnishings for a romantic, historic escape. Highly praised for personalized service and peaceful ambiance away from downtown hustle.

  • Historic monastery
  • Garden courtyard
  • Boutique charm
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Drury Inn & Suites Pittsburgh Airport Settlers Ridge — Airport Area
$
★ 9.3 Superb

Outstanding airport hotel with complimentary shuttle, expansive free breakfast, and 5:30 Kickback snacks including drinks for unbeatable value. Ideal for early flights or layovers, with spacious suites and consistent top ratings.

  • Airport shuttle
  • Free evening snacks
  • Spacious suites
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Omni William Penn Hotel — Downtown
$$$
★ 8.7 Fabulous

Pittsburgh's grand historic landmark since 1916, boasting opulent ballrooms, elegant rooms, and central location near theaters and shopping. A favorite for its classic luxury and storied past, perfect for special occasions.

  • Historic landmark
  • Elegant dining
  • Central location
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Fairmont Pittsburgh — Downtown
$$$$
★ 8.3 Very Good

Modern luxury tower with floor-to-ceiling views, full-service spa, and sophisticated dining in the heart of the business district. Appeals to discerning travelers seeking upscale amenities and skyline vistas.

  • Spa facilities
  • City views
  • Luxury suites
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Kimpton Hotel Monaco Pittsburgh — Downtown
$$$
★ 8.8 Fabulous

Eclectic boutique hotel in a restored 1910 post office building, pet-friendly with complimentary wine hour and yoga mats. Stands out for vibrant design and prime location near cultural attractions.

  • Pet friendly
  • Wine hour
  • Boutique style
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