Last updated: October 2026

Santorini — Traveler Guide

Best Spa & Wellness Hotels in Santorini (2026)

Hotels in Santorini with a spa and wellness centre, ranked by Booking.com guest score.

★ Our top pick

One of One Hotel

★ 9.7 Exceptional · Imerovigli

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Quick Answer

The Best Spa & Wellness Hotels in Santorini (2026) at a Glance

1. One of One Hotel · Imerovigli · ★ 9.7 Exceptional
2. Enarma Suites & Spa Wellness Retreat · Megalochori · ★ 9.7 Exceptional
3. Alleys All-Suite Hotel & Spa · Pyrgos · ★ 9.7 Exceptional
4. Cocoon Suites · Imerovigli · ★ 9.4 Superb
5. Santorini Princess Spa Hotel · Imerovigli · ★ 9.8 Exceptional

6 places · Checked October 2026

Our Picks

Best Spa & Wellness Hotels in Santorini (2026)

6 places · Checked October 2026

★ 9.7 Exceptional

Imerovigli

One of One Hotel

In Imerovigli. Guests score it 9.7 out of 10 across 437 Booking.com reviews. It has a spa and wellness centre, according to Booking.com.

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★ 9.7 guest score from 437 Booking.com reviews · Many rooms include free cancellation

★ 9.7 Exceptional

Megalochori

Enarma Suites & Spa Wellness Retreat

In Megalochori. Guests score it 9.7 out of 10 across 320 Booking.com reviews. It has a spa and wellness centre, according to Booking.com.

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★ 9.7 guest score from 320 Booking.com reviews · Many rooms include free cancellation

★ 9.7 Exceptional

Pyrgos

Alleys All-Suite Hotel & Spa

In Pyrgos. Guests score it 9.7 out of 10 across 491 Booking.com reviews. It has a spa and wellness centre, according to Booking.com.

Spa
Most reviewed

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★ 9.7 guest score from 491 Booking.com reviews · Many rooms include free cancellation

★ 9.4 Superb

Imerovigli

Cocoon Suites

In Imerovigli. Guests score it 9.4 out of 10 across 484 Booking.com reviews. It has a spa and wellness centre, according to Booking.com.

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★ 9.4 guest score from 484 Booking.com reviews · Many rooms include free cancellation

★ 9.8 Exceptional

Imerovigli

Santorini Princess Spa Hotel

In Imerovigli. Guests score it 9.8 out of 10 across 477 Booking.com reviews. It has a spa and wellness centre, according to Booking.com.

Spa
Top rated

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★ 9.8 guest score from 477 Booking.com reviews · Many rooms include free cancellation

★ 9.3 Superb

Imerovigli

Cresanto Luxury Suites

In Imerovigli. Guests score it 9.3 out of 10 across 485 Booking.com reviews. It has a spa and wellness centre, according to Booking.com.

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★ 9.3 guest score from 485 Booking.com reviews · Many rooms include free cancellation

About This Guide

How we picked: every place in this guide is one Booking.com lists with a spa and wellness centre, ranked by guest score and weighted by how many reviews it has. Policies can change, so confirm on the booking page before you pay. Checked in October 2026.

Insider Tips

1
Book signature treatments 2-3 weeks ahead, especially for weekend stays.
2
Arrive at the spa 30-45 minutes early to enjoy the thermal facilities.
3
Ask about multi-treatment packages — they often include complimentary access to facilities.
4
Hydrate well before and after treatments for the best results.

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All Santorini Hotels

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Common Questions

Frequently Asked Questions

What types of spa treatments are available?

Treatments range from traditional massages and facials to thermal circuit experiences, hydrotherapy, cryotherapy, and locally-inspired healing rituals unique to the region.

Do I need to book spa treatments in advance?

Yes, especially for popular treatments and weekends. Many hotels offer advance booking through their concierge or spa reception, often with discounts for early reservations.